SCHEMBL4388035

SCHEMBL4388035

CCCC(=O)OC[C@H](O)[C@H]1OC(O)=C(O)C1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
HSPD1 P10809 1/20 0.55
HSPE1 P61604 1/20 0.55
TST Q16762 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
NLRP3 Q96P20 2/20 0.39
PPM1A P35813 2/20 0.39
LMNA P02545 3/20 0.33
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ENPP2 Q13822 2/20 0.33
LPAR6 P43657 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR4 Q99677 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285433 0.90 MAPT (0.70) MAPTTDP1HSPD1HSPE1TST
SCHEMBL2460004 0.90 MAPT (0.70) MAPTTDP1HSPD1HSPE1TST
SCHEMBL23356552 0.90 MAPT (0.70) MAPTTDP1HSPD1HSPE1TST
SCHEMBL17817668 0.90 MAPT (0.70) MAPTTDP1HSPD1HSPE1TST
SCHEMBL4394073 0.81 MAPT (0.81) MAPTTDP1HSPD1HSPE1TST
SCHEMBL4574133 0.81 MAPT (0.81) MAPTTDP1HSPD1HSPE1TST
SCHEMBL4394069 0.81 MAPT (0.81) MAPTTDP1HSPD1HSPE1TST
SCHEMBL4394133 0.76 TSHR (0.40) MAPTTDP1HSPD1HSPE1TST
SCHEMBL1869725 0.76 MAPT (0.66) MAPTTDP1HSPD1HSPE1TST
SCHEMBL31676474 0.76 MAPT (0.66) MAPTTDP1HSPD1HSPE1TST

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629424-B2 Metal-containing compositions and method of making same PRYOG, LLC (US) 2009-12-08 US claimed
US-20080015278-A1 Metal-Containing Compositions and Method of Making Same PRYOG, LLC 2008-01-17 US claimed
WO-2007070092-A2 METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME PRYOG, LLC (US) 2007-06-21 WO claimed
US-7629424-B2 Metal-containing compositions and method of making same PRYOG, LLC (US) 2009-12-08 US disclosed
US-20080015278-A1 Metal-Containing Compositions and Method of Making Same PRYOG, LLC 2008-01-17 US disclosed
WO-2007070092-A2 METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME PRYOG, LLC (US) 2007-06-21 WO disclosed