Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL23796915 | 0.97 | KDM4E (0.50) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL16316781 | 0.87 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Synthalin SCHEMBL29526432 | 0.85 | MEN1 (0.52) | KDM4EMAPK1HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14598288 | 0.83 | KDM4E (0.65) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Trifluoroacetic Acid SCHEMBL3444104 | 0.82 | HDAC6 (0.42) | PAOXSMN1; SMN2ALDH1A1POLBCA3 | |
| Tiformin SCHEMBL7440384 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1POLBCA3CA5A | |
| SCHEMBL26218458 | 0.81 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Trifluoroacetic Acid SCHEMBL6762936 | 0.81 | SMN1; SMN2 (0.44) | ADRA1ASMN1; SMN2ALDH1A1POLBCA3 | |
| Agmatine SCHEMBL23364182 | 0.81 | PAOX (0.44) | PAOXSMN1; SMN2ALDH1A1POLBCA3 | |
| Trifluoroacetic Acid SCHEMBL27898251 | 0.80 | PAOX (0.62) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |