⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18268910 | 0.86 | LMNA (0.52) | — | |
| SCHEMBL18268935 | 0.84 | LMNA (0.50) | — | |
| SCHEMBL4134507 | 0.78 | LMNA (0.48) | — | |
| SCHEMBL31678757 | 0.76 | — | — | |
| SCHEMBL22905077 | 0.76 | — | — | |
| SCHEMBL23590740 | 0.76 | — | — | |
| SCHEMBL1331223 | 0.76 | — | — | |
| SCHEMBL880 | 0.76 | — | — | |
| SCHEMBL879 | 0.76 | — | — | |
| Water SCHEMBL23042868 | 0.75 | LMNA (0.96) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459942-B2 | Inhibiting (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| EP-4596230-A1 | MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME, AUTOMOBILE PART, AIRCRAFT PART, AND DAMPING MATERIAL FOR CARBON-FIBER-REINFORCED PLASTIC | Mitsubishi Chemical Corporation (JP) | 2025-08-06 | — | — | EP | disclosed |
| US-20250178327-A1 | MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME, AUTOMOBILE PART, AIRCRAFT PART, AND DAMPING MATERIAL FOR CARBON-FIBER-REINFORCED PLASTIC | MITSUBISHI CHEMICAL CORPORATION (JP) | 2025-06-05 | — | — | US | disclosed |
| EP-4502050-A1 | MODIFIED ETHYLENE-VINYL ALCOHOL COPOLYMER COMPOSITION, PELLET, MULTILAYER STRUCTURE, METHOD FOR PRODUCING MODIFIED ETHYLENE-VINYL ALCOHOL COPOLYMER COMPOSITION, AND METHOD FOR PRODUCING MULTILAYER STRUCTURE | Mitsubishi Chemical Corporation (JP) | 2025-02-05 | — | — | EP | disclosed |
| US-20240392105-A1 | MODIFIED ETHYLENE-VINYL ALCOHOL COPOLYMER COMPOSITION, PELLETS, MULTILAYER STRUCTURE, METHOD FOR PRODUCING MODIFIED ETHYLENE-VINYL ALCOHOL COPOLYMER COMPOSITION, AND METHOD FOR PRODUCING MULTILAYER STRUCTURE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-11-28 | — | — | US | disclosed |
| US-20240376095-A1 | INHIBITING (ALPHA-V)(BETA-6) INTEGRIN | SCHR¿DINGER, LLC | 2024-11-14 | — | — | US | disclosed |
| CN-118878533-A | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| US-12116369-B2 | Substituted pyrazolo[1,5-a]pyrimidines as glucocerebrosidase activators | Bial—R&D Investments, S.A. (PT) | 2024-10-15 | — | — | US | disclosed |
| EP-4410888-A1 | RESIN COMPOSITION, MOLDED ARTICLE, MODIFIER FOR ABS RESIN, METHOD FOR PRODUCING RESIN COMPOSITION, AND METHOD FOR MODIFYING ABS RESIN | Mitsubishi Chemical Corporation (JP) | 2024-08-07 | — | — | EP | disclosed |
| CN-112805001-B | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-07-23 | — | — | CN | disclosed |
| EP-0277052-B1 | 4,4-DIMETHYLTETRAHYDROPYR-2-ONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF PYRETRIN PRODUCTS | ROUSSEL-UCLAF (FR) | 1992-03-11 | — | — | EP | disclosed |
| WO-1991018885-A1 | IMIDAZOLES FOR THE TREATMENT OF ATHEROSCLEROSIS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0277052-A1 | 4,4-Dimethyltetrahydropyr-2-one derivatives, processes for their preparation and their use in the synthesis of pyretrin products | ROUSSEL-UCLAF (FR) | 1988-08-03 | — | — | EP | disclosed |
| EP-0277052-A1 | 4,4-Dimethyltetrahydropyr-2-one derivatives, processes for their preparation and their use in the synthesis of pyretrin products | ROUSSEL-UCLAF (FR) | 1988-08-03 | — | — | EP | disclosed |
| EP-0153212-B1 | 4,4-DIMETHYL TETRAHYDRO-2H-PYRAN-2-ON DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF CYCLOPROPANIC DERIVATIVES | ROUSSEL-UCLAF (FR) | 1988-07-13 | — | — | EP | disclosed |
| EP-0153212-B1 | 4,4-DIMETHYL TETRAHYDRO-2H-PYRAN-2-ON DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF CYCLOPROPANIC DERIVATIVES | ROUSSEL-UCLAF (FR) | 1988-07-13 | — | — | EP | disclosed |
| US-4562270-A | CATALYTIC HEATING OF HJYDROXY SUBSTITUTED FURANONE | DYNAMIT NOBEL AG (DE) | 1985-12-31 | — | — | US | disclosed |
| EP-0153212-A1 | 4,4-Dimethyl tetrahydro-2H-pyran-2-on derivatives, process for their preparation and their use for the preparation of cyclopropanic derivatives | ROUSSEL-UCLAF (FR) | 1985-08-28 | — | — | EP | disclosed |
| EP-0153212-A1 | 4,4-Dimethyl tetrahydro-2H-pyran-2-on derivatives, process for their preparation and their use for the preparation of cyclopropanic derivatives | ROUSSEL-UCLAF (FR) | 1985-08-28 | — | — | EP | disclosed |