Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187787 | 1.00 | ALDH1A1 (0.78) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL15078047 | 0.96 | ALDH1A1 (0.72) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL27988767 | 0.80 | ALDH1A1 (0.57) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL5593714 | 0.79 | ALDH1A1 (0.57) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL29182250 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL11836972 | 0.77 | MCL1 (0.54) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL6972926 | 0.77 | ALDH1A1 (0.59) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL13282510 | 0.76 | ALDH1A1 (0.54) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL11477851 | 0.75 | ALDH1A1 (0.59) | ALDH1A1POLBKDM4EHPGDL3MBTL1 | |
| SCHEMBL11475684 | 0.74 | CA1 (0.64) | ALDH1A1POLBKDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112274-B1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2009-12-09 | — | — | EP | disclosed |
| US-7422908-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-09-09 | — | — | US | disclosed |
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P (US) | 2004-04-22 | — | — | US | disclosed |
| US-20030213940-A1 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P (US) | 2003-11-20 | — | — | US | disclosed |
| US-6461876-B1 | STABLE SPIROFUSED RINGS; DECOMPOSING TO GENERATE LIGHT AND CARBONYL GROUP; HIGH ENERGY; MEDICINE | TOBEN, HOWARD R. | 2002-10-08 | — | — | US | disclosed |
| EP-1112274-A4 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1112274-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | Giri, Brij P. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000014092-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2000-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | CYP19A1, CYP1A1, CYP2F1 | ALDH1A1 289/4885POLB 1831/4885KDM4E 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.