SCHEMBL438943

SCHEMBL438943

C1=CC2NCNC2C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058581 0.79
SCHEMBL19610209 0.74
SCHEMBL21312207 0.70
SCHEMBL14138851 0.65
SCHEMBL4970931 0.64
SCHEMBL21312047 0.60 EGLN1 (0.33)
SCHEMBL2307623 0.57
SCHEMBL152393 0.57
SCHEMBL17104842 0.57
SCHEMBL17104885 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854708-A Synthesis method of tetrahydrobenzimidazolo [1,2,3] oxathiazine sulfone compound 邵阳学院 2023-10-10 CN claimed
CN-109641918-B Imidazoles as inhibitors of histone demethylases 欧洲肿瘤研究所有限责任公司 2021-12-21 CN claimed
US-7553854-B2 6-O-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2009-06-30 US claimed
EP-2010528-A2 6-O-SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE COMPOUNDS AND METHODS OF INHIBITING CSF-1R SIGNALING Novartis Pharma AG (CH) 2009-01-07 EP claimed
US-20080045528-A1 6-O-SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE COMPOUNDS AND METHODS OF INHIBITING CSF-1R SIGNALING NOVARTIS AG 2008-02-21 US claimed
WO-2007121484-A2 6-O-SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE COMPOUNDS AND METHODS OF INHIBITING CSF-1R SIGNALING NOVARTIS AG (CH) 2007-10-25 WO claimed
EP-0381422-B1 Tetrahydrobenzimidazole derivatives YAMANOUCHI PHARMA CO LTD (JP) 1996-10-23 EP claimed
US-5496942-A 5-HT3-RECEPTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1996-03-05 US claimed
US-5344927-A 5-HT3 antagonist YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1994-09-06 US claimed
EP-0381422-A1 Tetrahydrobenzimidazole derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1990-08-08 EP claimed
EP-0193307-B1 PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-08-09 EP claimed
US-4847251-A CARDIOVASCULAR DISORDERS BOEHRINGER MANNHEIM GMBH (DE) 1989-07-11 US claimed
US-4734415-A CARDIOTONIC, HYPOTENSIVE WARNER-LAMBERT COMPANY (US) 1988-03-29 US claimed
EP-0193307-A2 Process for the extraction of metal values and novel metal extractants IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-09-03 EP claimed
US-4550119-A 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones WARNER-LAMBERT COMPANY (US) 1985-10-29 US claimed
JP-7215969-A None JP disclosed
CN-116615332-B Optically anisotropic laminate and optical element MITSUBISHI CHEMICAL CORP. (JP) 2026-05-26 CN disclosed
US-3987054-A CORROSION INHIBITORS PLIVA PHARMACEUTICAL AND CHEMICAL WORKS (YU) 1976-10-19 US disclosed
US-3939125-A CURABLE CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed
US-3932444-A PLASTICIZERS E. I. DU PONT DE NEMOURS & CO. (US) 1976-01-13 US disclosed