⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14138851 | 0.81 | — | — | |
| SCHEMBL2188862 | 0.80 | — | — | |
| SCHEMBL6511319 | 0.78 | — | — | |
| SCHEMBL991862 | 0.72 | — | — | |
| SCHEMBL10347726 | 0.69 | — | — | |
| SCHEMBL14996956 | 0.69 | — | — | |
| SCHEMBL1724424 | 0.69 | — | — | |
| SCHEMBL16118519 | 0.63 | — | — | |
| SCHEMBL29666134 | 0.62 | — | — | |
| SCHEMBL8644805 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396191-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-07-10 | — | — | EP | claimed |
| CN-118076613-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2024-05-24 | — | — | CN | claimed |
| WO-2023033740-A9 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-12-28 | — | — | WO | claimed |
| WO-2023033740-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-03-09 | — | — | WO | claimed |
| US-20060100233-A1 | Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PFIZER ITALIA S.R.L. (IT) | 2006-05-11 | — | — | US | claimed |
| EP-1526852-A1 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2005-05-04 | — | — | EP | claimed |
| WO-2004014374-A1 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2004-02-19 | — | — | WO | claimed |
| EP-0148440-B1 | 1,3,4,5-TETRAHYDROBENZO(C,D)INDOLES, PROCESS FOR THEIR PREPARATION AND THEIR USES | Troponwerke GmbH & Co. KG (DE) | 1988-10-05 | — | — | EP | claimed |
| EP-0148440-A1 | 1,3,4,5-Tetrahydrobenzo(c,d)indoles, process for their preparation and their uses | Troponwerke GmbH & Co. KG (DE) | 1985-07-17 | — | — | EP | claimed |
| JP-4217662-A | — | — | None | — | — | JP | disclosed |
| EP-4396191-B1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2026-02-18 | — | — | EP | disclosed |
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-04-24 | — | — | US | disclosed |
| EP-4396191-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-07-10 | — | — | EP | disclosed |
| CN-118076613-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-4282240-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4282240-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4282240-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| EP-0029581-A2 | Amino substituted tetrahydrobenzindoles, a process for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029581-A2 | Amino substituted tetrahydrobenzindoles, a process for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029581-A2 | Amino substituted tetrahydrobenzindoles, a process for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1981-06-03 | — | — | EP | disclosed |