Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386333 | 0.88 | MAOB (0.59) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL4382266 | 0.86 | MAOA (0.58) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL4388934 | 0.85 | MAOA (0.45) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL13632912 | 0.81 | MAOA (0.47) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL4384627 | 0.81 | MAOA (0.47) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL4375836 | 0.80 | MAOA (0.43) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL4379544 | 0.79 | MAOA (0.50) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL13632910 | 0.76 | MAOA (0.63) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL4378817 | 0.76 | MAOA (0.63) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL4965827 | 0.74 | F10 (0.53) | F10MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899331-B1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2009-11-25 | — | — | EP | claimed |