Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247016 | 0.78 | TDP1 (0.50) | TDP1TSHRLMNAALDH1A1 | |
| SCHEMBL27981312 | 0.78 | TDP1 (0.50) | TDP1TSHRLMNAALDH1A1 | |
| SCHEMBL20577726 | 0.74 | LMNA (0.46) | TDP1TSHRLMNAALDH1A1 | |
| Propylene Glycol SCHEMBL9930705 | 0.70 | TDP1 (0.77) | TDP1TSHRLMNAALDH1A1 | |
| SCHEMBL3388764 | 0.67 | — | — | |
| SCHEMBL29022796 | 0.67 | — | — | |
| SCHEMBL2394452 | 0.67 | — | — | |
| SCHEMBL12319618 | 0.67 | — | — | |
| SCHEMBL270391 | 0.67 | — | — | |
| SCHEMBL20577856 | 0.67 | LMNA (0.44) | TDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306041-A1 | Inhibitors of Bruton's tyrosine kinase | ROCHE PALO ALTO LLC | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306041-A1 | Inhibitors of Bruton's tyrosine kinase | BTK, SYK, LYN | TDP1 322/4885TSHR 1637/4885LMNA 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.