SCHEMBL4390043

SCHEMBL4390043

Nc1ccc2nc(N)oc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.66
NPC1 O15118 8/20 0.61
RAB9A P51151 8/20 0.61
MAPT P10636 6/20 0.61
SMN1; SMN2 Q16637 6/20 0.61
KDM4E B2RXH2 6/20 0.61
ALDH1A1 P00352 4/20 0.61
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
HPGD P15428 3/20 0.61
GLA P06280 1/20 0.61
GAA P10253 1/20 0.61
LMNA P02545 3/20 0.50
CYP1A2 P05177 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
MAPK1 P28482 1/20 0.50
PIK3CB P42338 1/20 0.43
LCK P06239 1/20 0.43
GFER P55789 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6398262 0.83 MAPT (0.66) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL10950114 0.83 PIK3CG (0.66) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL15157800 0.79 NPC1 (0.58) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL9898426 0.79 PIK3CG (0.61) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL557792 0.79 PIK3CG (0.61) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL9896463 0.79 PIK3CG (1.00) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL7893733 0.79 PIK3CG (0.61) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL30988526 0.79 PIK3CG (0.61) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL21983971 0.79 PIK3CG (0.61) PIK3CGNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL615340 0.79 SMN1; SMN2 (0.58) PIK3CGNPC1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085329-A1 MULTIFUNCTIONAL ADHESION PROMOTER FOR SEMICONDUCTOR DEVICE PACKAGES WOLFSPEED, INC. (US) 2025-04-24 WO claimed
US-20250122413-A1 Multifunctional Adhesion Promoter for Semiconductor Device Packages U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2025-04-17 US claimed
CN-116333299-B Preparation method of polyol for waterborne polyurethane 上海蓝欧化工科技有限公司 2025-04-08 CN claimed
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US claimed
US-20240254284-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2024-08-01 US claimed
WO-2020232338-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 WO claimed
US-20200283580-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 US claimed
US-20090170914-A1 Cermide Kinase Modulation BORNANCIN FREDERIC 2009-07-02 US claimed
CN-101415695-A Ceramide kinase modulation NOVARTIS AG (CH) 2009-04-22 CN claimed
EP-2004617-A2 CERAMIDE KINASE MODULATION Novartis AG (CH) 2008-12-24 EP claimed
WO-2007112914-A2 CERAMIDE KINASE MODULATION NOVARTIS AG (CH) 2007-10-11 WO claimed
WO-2025085329-A1 MULTIFUNCTIONAL ADHESION PROMOTER FOR SEMICONDUCTOR DEVICE PACKAGES WOLFSPEED, INC. (US) 2025-04-24 WO disclosed
US-20250122413-A1 Multifunctional Adhesion Promoter for Semiconductor Device Packages U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2025-04-17 US disclosed
CN-116333299-B Preparation method of polyol for waterborne polyurethane 上海蓝欧化工科技有限公司 2025-04-08 CN disclosed
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US disclosed
CN-101415695-A Ceramide kinase modulation NOVARTIS AG (CH) 2009-04-22 CN disclosed
EP-2004617-A2 CERAMIDE KINASE MODULATION Novartis AG (CH) 2008-12-24 EP disclosed
WO-2007112914-A2 CERAMIDE KINASE MODULATION NOVARTIS AG (CH) 2007-10-11 WO disclosed
US-4321363-A Adsorbent for urokinase containing agarose NIPPON SODA COMPANY LIMITED (JP) 1982-03-23 US disclosed
US-4122117-A Indandione bis-azomethine pigments DAINIPPON INK & CHEMICALS, INC. (JP) 1978-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PUF60, FTO, PARN PIK3CG 768/4885NPC1 4844/4885RAB9A 3650/4885
US-20090170914-A1 Cermide Kinase Modulation CERS2, CHKB, SPHK2 PIK3CG 483/4885NPC1 247/4885RAB9A 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.