SCHEMBL4390195

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4378298	0.89	EGFR (0.41)	EGFRPTPN1ALDH1A1MAPTCAPN1
	SCHEMBL4389125	0.88	EGFR (0.42)	EGFRTSHRKDM4EMEN1ALDH1A1
	SCHEMBL4384148	0.86	EGFR (0.40)	EGFRTSHRPTPN1SRCCA12
	SCHEMBL4384158	0.86	EGFR (0.40)	EGFRTSHRPTPN1SRCCA12
	SCHEMBL4386891	0.84	EGFR (0.41)	EGFRALDH1A1GAAHSD17B10
	SCHEMBL4381129	0.83	EGFR (0.42)	EGFRMEN1KMT2ACAPN1
	SCHEMBL4389328	0.83	EGFR (0.38)	EGFRTSHRPTPN1SRCCA12
	SCHEMBL4385950	0.83	EGFR (0.43)	EGFRTSHRKDM4EMEN1ALDH1A1
	SCHEMBL2864914	0.83	EGFR (0.37)	EGFRKDM4EMAPTTDP1
	SCHEMBL4387418	0.82	EGFR (0.44)	EGFRKDM4EMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.