SCHEMBL4390528

SCHEMBL4390528

O=C(c1ccccc1C(=O)S(=O)(=O)O)S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
ALOX15 P16050 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.42
TSHR P16473 3/20 0.42
CA1 P00915 4/20 0.39
CA2 P00918 4/20 0.39
MAPT P10636 3/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.39
CA9 Q16790 3/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
CA12 O43570 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2806477 0.84 HPGD (0.46) ALDH1A1SMN1; SMN2TSHRKDM4EHPGD
SCHEMBL28589368 0.80 NR4A1 (0.59) ALDH1A1ALOX15SMN1; SMN2TSHRMAPT
SCHEMBL27360130 0.79 NR4A1 (0.57) ALDH1A1ALOX15SMN1; SMN2TSHRMAPT
SCHEMBL27636041 0.77 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2TSHRCA1CA2
SCHEMBL1728427 0.76 CES1 (0.50) ALDH1A1ALOX15SMN1; SMN2TSHRCA1
SCHEMBL6262061 0.75 ESR1 (0.45) ALDH1A1TSHRMAPTLMNAKDM4E
SCHEMBL28136722 0.74 CES1 (0.48) ALDH1A1ALOX15SMN1; SMN2TSHRCA1
Hydrochloric Acid SCHEMBL27590007 0.74 CES1 (0.48) ALDH1A1ALOX15SMN1; SMN2TSHRCA1
Fluoride SCHEMBL28016642 0.74 CES1 (0.48) ALDH1A1ALOX15SMN1; SMN2TSHRCA1
Phthalic Acid SCHEMBL3700659 0.72 ALDH1A1 (0.78) ALDH1A1ALOX15SMN1; SMN2TSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2097486-A2 TETRA-SULFO IRON-PHTHALOCYANINE AND RELATED METHODS Dow Global Technologies Inc. (US) 2009-09-09 EP disclosed
WO-2008079356-A2 TETRA-SULFO IRON-PHTHALOCYANINE AND RELATED METHODS DOW GLOBAL TECHNOLOGIES INC. (US) 2008-07-03 WO disclosed