Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397421 | 0.89 | DRD2 (0.56) | DRD2DRD3 | |
| SCHEMBL4402517 | 0.85 | DRD2 (0.58) | DRD2DRD3 | |
| SCHEMBL4521353 | 0.84 | DRD2 (0.62) | DRD2DRD3 | |
| SCHEMBL4390977 | 0.83 | DRD2 (0.58) | DRD2DRD3 | |
| SCHEMBL4390927 | 0.81 | DRD2 (0.63) | DRD2DRD3 | |
| SCHEMBL4397380 | 0.80 | DRD2 (0.65) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4524158 | 0.80 | DRD2 (0.62) | DRD2DRD3 | |
| SCHEMBL4388921 | 0.80 | DRD3 (0.62) | DRD2DRD3 | |
| SCHEMBL5174628 | 0.79 | DRD2 (0.63) | DRD2DRD3 | |
| SCHEMBL4390552 | 0.79 | DRD2 (0.62) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778684-B1 | 4-PIPERAZINYL-PYRIMIDINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D<sb>3</sb> RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2009-12-16 | — | — | EP | claimed |