Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.51 |
| ▸ | DRD3 | P35462 | 20/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4530655 | 0.99 | DRD2 (0.50) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL4399853 | 0.85 | DRD2 (0.50) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL4397216 | 0.85 | DRD2 (0.49) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4397256 | 0.85 | DRD2 (0.49) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL4399844 | 0.84 | DRD2 (0.51) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL4396041 | 0.83 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL4392911 | 0.83 | DRD2 (0.48) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4515168 | 0.83 | DRD2 (0.51) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL391471 | 0.83 | DRD2 (0.47) | DRD2DRD3 | |
| SCHEMBL4392026 | 0.83 | DRD2 (0.51) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778684-B1 | 4-PIPERAZINYL-PYRIMIDINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D<sb>3</sb> RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2009-12-16 | — | — | EP | disclosed |