SCHEMBL439174

SCHEMBL439174

CCCCCc1nc2ccccc2o1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.70
NPC1 O15118 2/20 0.70
RAB9A P51151 2/20 0.70
LOXL2 Q9Y4K0 1/20 0.62
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
TP53 P04637 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
GFER P55789 1/20 0.54
DRD3 P35462 6/20 0.51
DRD2 P14416 5/20 0.51
DRD4 P21917 3/20 0.51
PTGS2 P35354 1/20 0.48
DRD1 P21728 2/20 0.48
ELANE P08246 1/20 0.47
TLR8 Q9NR97 1/20 0.47
TLR7 Q9NYK1 1/20 0.47
FAAH O00519 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11623669 0.98 MAPT (0.68) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL28018741 0.98 MAPT (0.68) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL2567453 0.98 MAPT (0.68) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL28018181 0.98 MAPT (0.68) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL7793708 0.98 MAPT (0.68) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL14402606 0.98 MAPT (0.68) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL28018742 0.98 MAPT (0.68) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL30184671 0.95 RAB9A (0.72) MAPTNPC1RAB9ALOXL2KMT2A
SCHEMBL591905 0.95 RAB9A (0.72) MAPTNPC1RAB9ALOXL2KMT2A
Benzene SCHEMBL28280876 0.93 RAB9A (0.70) MAPTNPC1RAB9ALOXL2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116037152-B Palladium copper-cuprous oxide core-shell nano-cage catalyst and preparation method and application thereof 深圳大学 2024-07-16 CN claimed
CN-116037152-A Palladium copper-cuprous oxide core-shell nano-cage catalyst and preparation method and application thereof 深圳大学 2023-05-02 CN claimed
CN-116004637-A Method for catalyzing 2-alkyl and aryl benzoxazole derivatives by using double-enzyme system 吉林大学 2023-04-25 CN claimed
CN-115557911-A 2-keto aryl benzoxazole compounds and synthesis method thereof 海南大学 2023-01-03 CN claimed
CN-115557912-A 2-aryl benzoxazole compound and synthesis method thereof 海南大学 2023-01-03 CN claimed
CN-114149380-A Novel preparation method of 2-aryl benzoxazole series compounds 江西师范大学 2022-03-08 CN claimed
CN-111153870-A Synthetic method of 2-aryl benzoxazole derivative 湖南生物机电职业技术学院 2020-05-15 CN claimed
CN-104892539-B Novel synthesis method of iron-catalyzed 2-aryl benzoxazole compound 苏州大学 2017-12-22 CN claimed
WO-2016001682-A1 TREATMENT OF HYPERTRANSAMINASEMIA SUMMIT THERAPEUTICS PLC (GB) 2016-01-07 WO claimed
CN-104892539-A Novel synthesis method of iron-catalyzed 2-aryl benzoxazole compound UNIV SOOCHOW 2015-09-09 CN claimed
EP-0555460-A1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER. OREAL (FR) 1993-08-18 EP claimed
WO-1993004666-A1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER L'OREAL (FR) 1993-03-18 WO claimed
WO-1993004665-A1 FILTERING COSMETIC COMPOSITION CONTAINING A LIPOSOLUBLE FILTER POLYMER WITH HYDROCARBONATED STRUCTURE AND A FILTER SILICONE L'OREAL (FR) 1993-03-18 WO claimed
US-5102660-A For use in cosmetics L'OREAL (FR) 1992-04-07 US claimed
EP-0332988-A2 2-Aryl-benzoxazoles and 2'-hydroxybenzanilides BAYER AG (DE) 1989-09-20 EP claimed
US-4866159-A SUNSCREEN AGENTS L'OREAL (FR) 1989-09-12 US claimed
US-4504644-A SUNSCREEN AGENTS L'OREAL (FR) 1985-03-12 US claimed
US-4282309-A OXIME ESTER AGFA-GEVAERT, N.V. (BE) 1981-08-04 US claimed
EP-0014012-A1 Photosensitive composition containing an ethylenically unsaturated compound, initiator and sensitizer AGFA-GEVAERT N.V. (BE) 1980-08-06 EP claimed
US-4107169-A BY REACTING TRICHLOROMETHYL AROMATIC COMPOUND WITH O-HYDROXY- OR O-MERCAPTOAROMATIC AMINE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-08-15 US claimed