Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 7/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28212107 | 0.85 | TDP1 (0.65) | CA12CA2CA9CYP3A4CA14 | |
| SCHEMBL11591708 | 0.84 | ESR1 (0.57) | CA12CA2CA9CYP3A4CA14 | |
| SCHEMBL9065620 | 0.84 | ESR1 (0.57) | CA12CA2CA9CYP3A4CA14 | |
| Phenol SCHEMBL7192832 | 0.82 | ALDH1A1 (0.54) | CA12CA2CA9CYP3A4CA14 | |
| SCHEMBL2386542 | 0.79 | CYP3A4 (0.48) | CA12CA2CA9CYP3A4CA14 | |
| Tert-Butylbenzene SCHEMBL5269369 | 0.79 | CYP3A4 (0.55) | CA12CA2CA9CYP3A4CA14 | |
| SCHEMBL32685466 | 0.79 | CYP3A4 (0.48) | CA12CA2CA9CYP3A4CA14 | |
| SCHEMBL26632885 | 0.79 | CYP1A2 (0.56) | CYP3A4ALDH1A1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL30536498 | 0.79 | CYP1A2 (0.56) | CYP3A4ALDH1A1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL29427097 | 0.78 | HDAC4 (0.57) | CA12CA2CA9CYP3A4CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203041-B1 | METHOD FOR PRODUCING MODIFIED POLYCARBONATES | BAYER MATERIALSCIENCE AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| CN-1211414-C | polycarbonate and molded article thereof | BAYER AG (DE) | 2005-07-20 | — | — | CN | disclosed |
| EP-1203042-B1 | POLYCARBONATE AND MOLDED POLYCARBONATE ARTICLES | BAYER MATERIALSCIENCE AG (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-6740730-B1 | CHAIN TERMINIATED, SOLVENT FREE, LOW BRANCHING, THERMOPLASTIC; STABILITY; TRANSPARENT | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-25 | — | — | US | disclosed |
| US-6596840-B1 | By reacting diphenol, carbonic acid dieseter and alkylphenol chain terminator using phosphonium salt catalyst; ester interchange | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| CN-1361803-A | polycarbonate and molded article thereof | BAYER AG (DE) | 2002-07-31 | — | — | CN | disclosed |
| EP-1203041-A1 | METHOD FOR PRODUCING MODIFIED POLYCARBONATES | Bayer Aktiengesellschaft (DE) | 2002-05-08 | — | — | EP | disclosed |
| EP-1203042-A1 | POLYCARBONATE AND MOLDED POLYCARBONATE ARTICLES | Bayer Aktiengesellschaft (DE) | 2002-05-08 | — | — | EP | disclosed |
| CN-1282340-A | Solid catalysts for polymerization of olefins and process for production of olefin polymers therewith | MARUZEN PETROCHEM CO LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
| WO-2001005866-A1 | METHOD FOR PRODUCING MODIFIED POLYCARBONATES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
| WO-2001005867-A1 | POLYCARBONATE AND MOLDED POLYCARBONATE ARTICLES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |