⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390485 | 0.81 | CYP1A2 (0.49) | — | |
| SCHEMBL4393564 | 0.78 | CYP1A2 (0.54) | — | |
| SCHEMBL14615629 | 0.75 | — | — | |
| SCHEMBL7493544 | 0.71 | — | — | |
| SCHEMBL7515683 | 0.69 | CA1 (0.43) | — | |
| SCHEMBL1873266 | 0.69 | CA1 (0.35) | — | |
| SCHEMBL28064716 | 0.67 | CYP1A2 (0.60) | — | |
| SCHEMBL14144051 | 0.67 | — | — | |
| SCHEMBL9608918 | 0.67 | — | — | |
| SCHEMBL36360 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090305239-A1 | Methods and compositions for determing a level of biologically active serum paraoxonase | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2009-12-10 | — | — | US | disclosed |
| US-20090305239-A1 | Methods and compositions for determing a level of biologically active serum paraoxonase | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2009-12-10 | — | — | US | disclosed |
| US-20090305239-A1 | Methods and compositions for determing a level of biologically active serum paraoxonase | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2009-12-10 | — | — | US | disclosed |
| EP-1915457-A2 | METHODS AND COMPOSITIONS FOR DETERMINING A LEVEL OF BIOLOGICALLY ACTIVE SERUM PARAOXONASE | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007020632-A2 | METHODS AND COMPOSITIONS FOR DETERMINING A LEVEL OF BIOLOGICALLY ACTIVE SERUM PARAOXONASE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2007-02-22 | — | — | WO | disclosed |