⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392084 | 0.71 | — | — | |
| SCHEMBL7515683 | 0.70 | CA1 (0.43) | — | |
| SCHEMBL4394465 | 0.67 | F2 (0.45) | — | |
| SCHEMBL2679865 | 0.67 | — | — | |
| SCHEMBL4390485 | 0.66 | CYP1A2 (0.49) | — | |
| SCHEMBL16120995 | 0.66 | CA1 (0.55) | — | |
| SCHEMBL6854823 | 0.66 | CA1 (0.55) | — | |
| SCHEMBL6857004 | 0.66 | CA1 (0.55) | — | |
| SCHEMBL7643331 | 0.66 | CA1 (0.55) | — | |
| SCHEMBL9973225 | 0.66 | CA1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707023-A1 | Method for the preparation of a heterocyclic polymer | DSM N.V. (NL) | 1996-04-17 | — | — | EP | claimed |
| US-6066666-A | OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX | WASHINGTON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |
| US-5776959-A | Anticonvulsant and anxiolytic lactam and thiolactam derivatives | WASHINGTON UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0707023-A1 | Method for the preparation of a heterocyclic polymer | DSM N.V. (NL) | 1996-04-17 | — | — | EP | disclosed |