Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 12/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392381 | 0.85 | LRRK2 (0.55) | LRRK2ALK | |
| SCHEMBL4562782 | 0.80 | ALK (0.72) | ALK | |
| SCHEMBL1613297 | 0.78 | PTK2 (0.51) | LRRK2ALKTTK | |
| SCHEMBL1612486 | 0.78 | LRRK2 (0.51) | LRRK2ALKTTK | |
| SCHEMBL1613415 | 0.72 | PTK2 (0.61) | LRRK2ALKTTK | |
| SCHEMBL7450144 | 0.71 | LRRK2 (1.00) | LRRK2TTK | |
| SCHEMBL7454644 | 0.71 | LRRK2 (0.85) | LRRK2TTK | |
| SCHEMBL7446915 | 0.69 | LRRK2 (1.00) | LRRK2TTK | |
| SCHEMBL27403041 | 0.69 | PTK2 (0.57) | LRRK2TTK | |
| SCHEMBL17644570 | 0.69 | LRRK2 (0.83) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306067-A1 | 2, 4-DIAMINOPYRIMIDIDE DERIVATES AND THEIR USE FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306067-A1 | 2, 4-DIAMINOPYRIMIDIDE DERIVATES AND THEIR USE FOR THE TREATMENT OF CANCER | MKI67, CCND1, CCNT1 | LRRK2 3110/4885ALK 455/4885TTK 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.