Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541916 | 0.86 | STIM1 (0.41) | DRD2DRD3 | |
| SCHEMBL19869251 | 0.86 | GRM5 (0.43) | GRM5GRM1 | |
| SCHEMBL4550543 | 0.81 | KEAP1 (0.48) | — | |
| SCHEMBL4379917 | 0.81 | HSP90AA1 (0.45) | — | |
| SCHEMBL18029589 | 0.77 | FLT3 (0.50) | — | |
| SCHEMBL4540995 | 0.76 | CYP19A1 (0.49) | — | |
| SCHEMBL20533135 | 0.76 | GRM5 (0.44) | GRM5GRM1 | |
| SCHEMBL20532909 | 0.76 | KDM1A (0.45) | — | |
| SCHEMBL4544162 | 0.74 | S1PR1 (0.44) | — | |
| SCHEMBL4061551 | 0.74 | CD74 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |