Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 19/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4396927 | 0.99 | NOTUM (0.53) | NOTUMKDM4EGAARXFP1 | |
| SCHEMBL4394676 | 0.71 | NOTUM (0.51) | NOTUMKDM4EGAA | |
| SCHEMBL18395243 | 0.71 | NOTUM (1.00) | NOTUM | |
| SCHEMBL13050395 | 0.71 | NOTUM (0.67) | NOTUMKDM4ERXFP1 | |
| SCHEMBL8270247 | 0.71 | NOTUM (1.00) | NOTUM | |
| SCHEMBL2291570 | 0.71 | NOTUM (0.67) | NOTUM | |
| Hydrochloric Acid SCHEMBL4404537 | 0.70 | NOTUM (0.50) | NOTUMKDM4EGAA | |
| SCHEMBL5542637 | 0.69 | NOTUM (1.00) | NOTUMKDM4ERXFP1 | |
| SCHEMBL2853839 | 0.69 | KDM4E (0.42) | KDM4E | |
| SCHEMBL13050396 | 0.69 | NOTUM (0.63) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |