Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 11/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4404537 | 0.99 | NOTUM (0.50) | NOTUMKAT6AGAACTSVCTSL | |
| SCHEMBL14482401 | 0.78 | NOTUM (0.55) | NOTUMKAT6AGAACTSVCTSL | |
| SCHEMBL2823140 | 0.76 | NOTUM (0.58) | NOTUMKAT6ACTSVCTSLCTSS | |
| SCHEMBL21795694 | 0.76 | NOTUM (0.75) | NOTUMGAAALDH1A1HPGDMAPK1 | |
| SCHEMBL2853839 | 0.72 | KDM4E (0.42) | ALDH1A1KDM4E | |
| SCHEMBL859977 | 0.72 | NOTUM (0.64) | NOTUMKAT6AALDH1A1HPGDMAPK1 | |
| SCHEMBL942003 | 0.72 | NOTUM (0.64) | NOTUMGAAALDH1A1HPGDMAPK1 | |
| SCHEMBL31291162 | 0.72 | NOTUM (0.64) | NOTUMKAT6AALDH1A1HPGDMAPK1 | |
| SCHEMBL4392566 | 0.71 | NOTUM (0.55) | NOTUMGAAKDM4E | |
| Hydrochloric Acid SCHEMBL4396927 | 0.70 | NOTUM (0.53) | NOTUMGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |