Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397831 | 0.96 | FFAR1 (0.66) | FFAR1CYSLTR2CYSLTR1FFAR4AKR1B1 | |
| SCHEMBL5763262 | 0.89 | FFAR1 (0.70) | FFAR1CYSLTR2CYSLTR1FFAR4CYP4F2 | |
| SCHEMBL4391107 | 0.88 | SMPD1 (0.54) | FFAR1CYSLTR2CYSLTR1FFAR4AKR1B1 | |
| SCHEMBL5848310 | 0.86 | PPARA (0.57) | FFAR1CYSLTR2CYSLTR1FFAR4AKR1B1 | |
| SCHEMBL4847215 | 0.85 | CYSLTR2 (0.69) | FFAR1CYSLTR2CYSLTR1FFAR4AKR1B1 | |
| SCHEMBL8339114 | 0.84 | FFAR1 (0.78) | FFAR1FFAR4AKR1B1PTGER4PTGER3 | |
| SCHEMBL4391093 | 0.84 | SMPD1 (0.55) | FFAR1FFAR4AKR1B1CYP4F2CYP4A11 | |
| SCHEMBL2772855 | 0.83 | FFAR1 (0.83) | FFAR1FFAR4AKR1B1CYP4F2CYP4A11 | |
| SCHEMBL4396421 | 0.83 | MMP12 (0.58) | FFAR1FFAR4AKR1B1CYP4F2CYP4A11 | |
| SCHEMBL17413684 | 0.83 | FFAR1 (0.80) | FFAR1FFAR4AKR1B1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067109-B1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-12-09 | — | — | EP | claimed |
| US-20050250824-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2005-11-10 | — | — | US | claimed |
| US-20030153579-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2003-08-14 | — | — | US | claimed |
| EP-1067109-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | claimed |
| EP-1067109-B1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-12-09 | — | — | EP | disclosed |
| EP-1067109-B1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-12-09 | — | — | EP | disclosed |
| US-7211591-B2 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7211591-B2 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7211591-B2 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7037914-B2 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050250824-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2005-11-10 | — | — | US | disclosed |
| US-20030153579-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2003-08-14 | — | — | US | disclosed |
| US-6506757-B1 | A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative, is useful as a hypoglycemic agent, a hypolipidemic agent, a preventive and/or a remedy for diseases associating metabolic disorders | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1067109-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153579-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | PPARA, PPARG, PPARD | FFAR1 9/4885CYSLTR2 3820/4885CYSLTR1 2345/4885 |
| US-20050250824-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | PPARA, PPARG, PPARD | FFAR1 12/4885CYSLTR2 3944/4885CYSLTR1 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.