⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599847 | 1.00 | — | — | |
| SCHEMBL30526988 | 0.83 | — | — | |
| SCHEMBL22612250 | 0.81 | — | — | |
| SCHEMBL8820207 | 0.78 | NPC1 (0.32) | — | |
| SCHEMBL22612420 | 0.75 | NPC1 (0.33) | — | |
| SCHEMBL28409304 | 0.74 | — | — | |
| SCHEMBL525584 | 0.73 | — | — | |
| SCHEMBL1274 | 0.73 | — | — | |
| SCHEMBL3259733 | 0.73 | — | — | |
| SCHEMBL28761094 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7082252-A | — | — | None | — | — | JP | disclosed |
| CN-101321525-B | Heteroaryl substituted piperidine derivatives as L-CPT1 inhibitors | HOFFMANN LA ROCHE | 2013-01-30 | — | — | CN | disclosed |
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |
| CN-101321525-A | Heteroaryl substituted piperidine derivatives as L-CPT1 inhibitors | HOFFMANN LA ROCHE (CH) | 2008-12-10 | — | — | CN | disclosed |
| EP-1373264-B1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LTD (GB) | 2004-12-22 | — | — | EP | disclosed |
| EP-0879229-A1 | ARYLPYRAZOLE INSECTICIDES | Takeda Chemical Industries, Ltd. (JP) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997028126-A1 | ARYLPYRAZOLE INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-07 | — | — | WO | disclosed |
| JP-H0782252-A | PRODUCTION OF IMIDIC ACID ESTER COMPOUND AND N-PYRAZOLYLAMIDOXIME COMPOUND | FUJI PHOTO FILM CO LTD | 1995-03-28 | — | — | JP | disclosed |