Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.66 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.59 |
| ▸ | CCR3 | P51677 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2071149 | 0.95 | HPGDS (0.62) | HPGDSMCHR1CCR3SSTR5 | |
| SCHEMBL2072112 | 0.95 | HPGDS (0.62) | HPGDSMCHR1CCR3SSTR5 | |
| SCHEMBL2073328 | 0.94 | HPGDS (0.65) | HPGDSMCHR1CCR3POLBSSTR5 | |
| SCHEMBL2070206 | 0.94 | HPGDS (0.65) | HPGDSMCHR1CCR3ACHEPOLB | |
| SCHEMBL2071099 | 0.94 | HPGDS (0.61) | HPGDSMCHR1CCR3ACHESSTR5 | |
| SCHEMBL2071664 | 0.94 | HPGDS (0.64) | HPGDSMCHR1CCR3POLBSSTR5 | |
| SCHEMBL2073464 | 0.94 | HPGDS (0.64) | HPGDSMCHR1CCR3SSTR5 | |
| SCHEMBL2073983 | 0.93 | HPGDS (0.60) | HPGDSMCHR1CCR3POLBSSTR5 | |
| SCHEMBL2071134 | 0.93 | HPGDS (0.63) | HPGDSMCHR1CCR3POLBSSTR5 | |
| SCHEMBL2073594 | 0.93 | HPGDS (0.63) | HPGDSMCHR1CCR3ACHESSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129660-A2 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | Pfizer Products Inc. (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008075172-A2 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |