Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4381098 | 0.95 | CCR1 (0.40) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4387634 | 0.95 | CCR1 (0.40) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL4585013 | 0.95 | CCR1 (0.43) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL4585864 | 0.92 | CCR1 (0.42) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL14884090 | 0.83 | CCR1 (0.33) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL10032260 | 0.81 | SMN1; SMN2 (0.36) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL23456655 | 0.79 | CCR1 (0.32) | CCR1RAB9ACCR5 | |
| SCHEMBL10032281 | 0.79 | SMN1; SMN2 (0.35) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL14082010 | 0.79 | LMNA (0.61) | CCR1CCR5KDM4EALDH1A1LMNA | |
| SCHEMBL10032391 | 0.79 | CCR1 (0.32) | CCR1RAB9ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629431-B2 | Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20080064847-A1 | Oxidative carbonylation; molecular weight control | IDEMISU KOSAN CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |