Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 9/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL928015 | 0.86 | ALDH1A1 (0.53) | RECQLPOLBTDP1KDM4EESR2 | |
| SCHEMBL929668 | 0.80 | ALDH1A1 (0.51) | RECQLPOLBTDP1KDM4EESR2 | |
| SCHEMBL927955 | 0.77 | TDP1 (0.46) | RECQLPOLBTDP1KDM4EESR2 | |
| SCHEMBL929441 | 0.76 | ALDH1A1 (0.55) | RECQLPOLBTDP1ESR2KMT2A | |
| SCHEMBL929875 | 0.75 | GRM5 (0.46) | RECQLPOLBTDP1KDM4EESR2 | |
| SCHEMBL929667 | 0.74 | ALDH1A1 (0.55) | RECQLPOLBTDP1ESR2KMT2A | |
| SCHEMBL928585 | 0.73 | ALDH1A1 (0.53) | RECQLPOLBTDP1KDM4EESR2 | |
| SCHEMBL3816843 | 0.71 | NR1H2 (0.36) | POLBTDP1KDM4EESR2RAB9A | |
| SCHEMBL929943 | 0.70 | RECQL (0.48) | RECQLPOLBTDP1KDM4EESR2 | |
| SCHEMBL929538 | 0.70 | GRM5 (0.44) | RECQLPOLBTDP1KDM4EESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085398-A1 | Pyrazolopyrimidines, a process for their preparation and their use as medicine | Merz Pharma GmbH & Co. KGaA (DE) | 2009-08-05 | — | — | EP | disclosed |