Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156046 | 0.90 | HTR6 (0.52) | HTR6PKMPKLR | |
| SCHEMBL3157140 | 0.90 | HTR6 (0.59) | HTR6EPHX2CTSSOXTR | |
| SCHEMBL3142711 | 0.89 | HTR6 (0.49) | HTR6ALDH1A1HTR2AHTR2CPKM | |
| SCHEMBL3138534 | 0.89 | HTR6 (0.49) | HTR6HTR2AHTR2CPKM | |
| SCHEMBL3138848 | 0.89 | HTR6 (0.51) | HTR6PKMPKLRCTSSOXTR | |
| SCHEMBL3145187 | 0.89 | HTR6 (0.58) | HTR6 | |
| SCHEMBL3144633 | 0.88 | HTR6 (0.51) | HTR6TSHR | |
| SCHEMBL3143032 | 0.88 | HTR6 (0.57) | HTR6CTSSOXTR | |
| SCHEMBL3152344 | 0.87 | HTR6 (0.55) | HTR6ALDH1A1PKMCTSSOXTR | |
| SCHEMBL3139646 | 0.87 | HTR6 (0.55) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |