Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752791 | 0.87 | TYR (0.58) | HTR2BCYP3A4TSHRMAPTTYR | |
| SCHEMBL4394169 | 0.83 | ESR2 (0.46) | HTR2BCYP3A4RECQLTSHRTYR | |
| SCHEMBL11796041 | 0.81 | TYR (0.58) | HTR2CCYP3A4TSHRMAPTTYR | |
| SCHEMBL10938397 | 0.81 | TYR (0.58) | HTR2CCYP3A4TSHRMAPTTYR | |
| SCHEMBL2328433 | 0.81 | TYR (0.52) | CYP3A4RECQLTSHRMAPTTYR | |
| SCHEMBL31553272 | 0.81 | TYR (0.52) | CYP3A4RECQLTSHRMAPTTYR | |
| SCHEMBL28108641 | 0.79 | TYR (0.45) | HTR2BCYP3A4RECQLTSHRMAPT | |
| SCHEMBL28028515 | 0.79 | TYR (0.45) | HTR2BCYP3A4TSHRMAPTTYR | |
| SCHEMBL855681 | 0.78 | TAAR1 (0.69) | TAAR1HTR2ACYP1A2HTR1DKDM4E | |
| SCHEMBL30251350 | 0.78 | TAAR1 (0.69) | TAAR1HTR2ACYP1A2HTR1DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110536693-B | PD1-41BBL fusion proteins and methods of using the same | 卡尔医学有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-110573522-B | SIRP alpha-41 BBL fusion proteins and methods of use thereof | 卡尔医学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-106995410-A | A kind of lactam derivative and its application | 江苏恩华药业股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| US-8227390-B2 | Binder resin for friction material, binder resin composition for friction material, composite material for friction material containing the same, friction material and production method thereof | AKEBONO BRAKE INDUSTRY CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20090137434-A1 | BINDER RESIN FOR FRICTION MATERIAL, BINDER RESIN COMPOSITION FOR FRICTION MATERIAL, COMPOSITE MATERIAL FOR FRICTION MATERIAL CONTAINING THE SAME, FRICTION MATERIAL AND PRODUCTION METHOD THEREOF | AKEBONO BRAKE INDUSTRY CO., LTD (JP) | 2009-05-28 | — | — | US | disclosed |