Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752791 | 0.87 | TYR (0.58) | TYRESR2ESR1MEN1KMT2A | |
| SCHEMBL27885749 | 0.83 | CYP3A4 (0.41) | TYRESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL31553272 | 0.81 | TYR (0.52) | TYRESR2ESR1MEN1KMT2A | |
| SCHEMBL10938397 | 0.81 | TYR (0.58) | TYRESR2ESR1MEN1KMT2A | |
| SCHEMBL2328433 | 0.81 | TYR (0.52) | TYRESR2ESR1MEN1KMT2A | |
| SCHEMBL11796041 | 0.81 | TYR (0.58) | TYRESR2ESR1MEN1KMT2A | |
| SCHEMBL4393973 | 0.79 | TAAR1 (0.52) | TYRESR2ESR1MEN1KMT2A | |
| SCHEMBL28108641 | 0.79 | TYR (0.45) | TYRESR2ESR1MEN1KMT2A | |
| SCHEMBL29712517 | 0.78 | TAAR1 (0.42) | MEN1KMT2ATP53MAPTHTT | |
| SCHEMBL7061982 | 0.78 | TAAR1 (0.42) | MEN1KMT2ATP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209448-A | Tricyclic compounds and uses thereof | SK CHEMICALS CO LTD | 2015-12-30 | — | — | CN | disclosed |