Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.78 |
| ▸ | PGR | P06401 | 2/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.78 |
| ▸ | HTR1A | P08908 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | GC | P02774 | 1/20 | 0.71 |
| ▸ | RXRA | P19793 | 1/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ercalcitriol SCHEMBL12922723 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL17274136 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL264876 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL264875 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL4398182 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL23142603 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL8776000 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL9050396 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL21433255 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL17274137 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11926583-B2 | Stabilized 1, 25-dihydroxyvitamin D2 and method of making same | EIRGEN PHARMA LTD. (IE) | 2024-03-12 | — | — | US | claimed |
| WO-1985002189-A1 | 1,25-DIHDROXYVITAMIN D2 COMPOUNDS AND METHODS FOR THEIR PREPARATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-05-23 | — | — | WO | claimed |
| US-11926583-B2 | Stabilized 1, 25-dihydroxyvitamin D2 and method of making same | EIRGEN PHARMA LTD. (IE) | 2024-03-12 | — | — | US | disclosed |
| EP-3026042-B1 | STABILIZED 1,25-DIHYDROXYVITAMIN D2 AND METHOD OF MAKING SAME | OPKO IRELAND GLOBAL HOLDINGS LTD (IE) | 2019-10-09 | — | — | EP | disclosed |
| EP-3026042-A1 | STABILIZED 1,25-DIHYDROXYVITAMIN D2 AND METHOD OF MAKING SAME | OPKO Ireland Global Holdings, Limited (IE) | 2016-06-01 | — | — | EP | disclosed |
| EP-2262765-B1 | STABILIZED 1,25-DIHYDROXYVITAMIN D2 AND METHOD OF MAKING SAME | OPKO IRELAND GLOBAL HOLDINGS LTD (IE) | 2016-03-09 | — | — | EP | disclosed |
| US-20140113886-A1 | Stabilized 1, 25-Dihydroxyvitamin D2 and Method of Making Same | CYTOCHROMA INC. (CA) | 2014-04-24 | — | — | US | disclosed |
| US-20090233889-A1 | STABILIZED 1,25-DIHYDROXYVITAMIN D2 AND METHOD OF MAKING SAME | EIRGEN PHARMA LTD. (IE) | 2009-09-17 | — | — | US | disclosed |
| WO-1985002189-A1 | 1,25-DIHDROXYVITAMIN D2 COMPOUNDS AND METHODS FOR THEIR PREPARATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-05-23 | — | — | WO | disclosed |