Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM6A | O15550 | 1/20 | 0.58 |
| ▸ | KDM4A | O75164 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM5C | P41229 | 1/20 | 0.58 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.58 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.58 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | COMT | P21964 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 10/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5136933 | 0.89 | APP (0.58) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9247282 | 0.88 | APP (0.57) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8102120 | 0.88 | APP (0.57) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8102009 | 0.86 | APP (0.56) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9513592 | 0.85 | APP (0.61) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL10359200 | 0.85 | APP (0.61) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL5085644 | 0.85 | KDM4E (0.58) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL12288571 | 0.84 | KDM4E (0.50) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9521632 | 0.84 | KDM4E (0.57) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL2511741 | 0.84 | KDM4E (0.57) | KDM4ETP53CYP2D6HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613560-B2 | A METHOD FOR ASSAYING AND TREATING ALZHEIMER'S DISEASE | PRANA BIOTECHNOLOGY LTD (AU) | 2006-06-21 | — | — | EP | claimed |
| US-20040265847-A1 | Method for treating Alzheimer's disease | MASTERS COLIN LOUIS | 2004-12-30 | — | — | US | claimed |
| US-RE35948-E | TREATING TOXIC METAL CONCENTRATION BY ADMINISTERING N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR 3-HYDROXYPYRID-4-ONE | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1998-11-03 | — | — | US | claimed |
| EP-0613560-B1 | A METHOD FOR ASSAYING AND TREATING ALZHEIMER'S DISEASE | UNIV MELBOURNE (AU) | 1998-10-21 | — | — | EP | claimed |
| EP-0305646-B1 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BRITISH TECH GROUP (GB) | 1996-11-13 | — | — | EP | claimed |
| EP-0613560-A4 | A METHOD FOR ASSAYING AND TREATING ALZHEIMER'S DISEASE. | UNIV MELBOURNE (AU) | 1995-05-17 | — | — | EP | claimed |
| EP-0613560-A1 | A METHOD FOR ASSAYING AND TREATING ALZHEIMER'S DISEASE | THE UNIVERSITY OF MELBOURNE (AU) | 1994-09-07 | — | — | EP | claimed |
| EP-0397409-B1 | THE STABILIZATION OF ORGANIC COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1993-07-21 | — | — | EP | claimed |
| WO-1993010459-A1 | A METHOD FOR ASSAYING AND TREATING ALZHEIMER'S DISEASE | THE UNIVERSITY OF MELBOURNE (AU) | 1993-05-27 | — | — | WO | claimed |
| EP-0397409-A1 | The stabilization of organic compounds | BTG INTERNATIONAL LIMITED (GB) | 1990-11-14 | — | — | EP | claimed |
| EP-0305646-A2 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1989-03-08 | — | — | EP | claimed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | claimed |
| US-8475768-B2 | Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) | GE HEALTHCARE AS (NO) | 2013-07-02 | — | — | US | disclosed |
| US-8459787-B2 | Aqueous inkjet printing fluid compositions | EASTMAN KODAK COMPANY (US) | 2013-06-11 | — | — | US | disclosed |
| US-8459787-B2 | Aqueous inkjet printing fluid compositions | EASTMAN KODAK COMPANY (US) | 2013-06-11 | — | — | US | disclosed |
| US-20120105553-A1 | AQUEOUS INKJET PRINTING FLUID COMPOSITIONS | KODAK (NEAR EAST) INC. | 2012-05-03 | — | — | US | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | disclosed |
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |