Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM6A | O15550 | 1/20 | 0.55 |
| ▸ | KDM4A | O75164 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM5C | P41229 | 1/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.55 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.55 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.55 |
| ▸ | COMT | P21964 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9247282 | 0.98 | APP (0.57) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL8102120 | 0.95 | APP (0.57) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL8102009 | 0.93 | APP (0.56) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL4394165 | 0.89 | KDM4E (0.58) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL10359200 | 0.89 | APP (0.61) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL9513592 | 0.89 | APP (0.61) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL7152347 | 0.86 | APP (0.58) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL3290957 | 0.85 | APP (0.57) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL9354571 | 0.85 | APP (0.57) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL9476440 | 0.83 | KDM4E (0.43) | APPHRH3KDM4ETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1978997-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | Apollo Life Sciences Limited (AU) | 2008-10-15 | — | — | EP | claimed |
| US-20070243132-A1 | Transdermal delivery of pharmaceutical agents | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-10-18 | — | — | US | claimed |
| WO-2007070983-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-06-28 | — | — | WO | claimed |
| US-RE35948-E | TREATING TOXIC METAL CONCENTRATION BY ADMINISTERING N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR 3-HYDROXYPYRID-4-ONE | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1998-11-03 | — | — | US | claimed |
| EP-0305646-B1 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BRITISH TECH GROUP (GB) | 1996-11-13 | — | — | EP | claimed |
| EP-0644761-A1 | HYDROXYPYRIDIN-4-ONES FOR TREATMENT OF PARASITICAL INFECTIONS | BTG INTERNATIONAL LIMITED (GB) | 1995-03-29 | — | — | EP | claimed |
| WO-1993021919-A1 | HYDROXYPYRIDIN-4-ONES FOR TREATMENT OF PARASITICAL INFECTIONS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-11-11 | — | — | WO | claimed |
| US-5256676-A | 3-hydroxy-pyridin-4-ones useful for treating parasitic infections | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-10-26 | — | — | US | claimed |
| EP-0397409-B1 | THE STABILIZATION OF ORGANIC COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1993-07-21 | — | — | EP | claimed |
| EP-0397409-A1 | The stabilization of organic compounds | BTG INTERNATIONAL LIMITED (GB) | 1990-11-14 | — | — | EP | claimed |
| WO-2011131474-A2 | SKIN-GENTLE DEODORANTS AND ANTIPERSPIRANTS | HENKEL AG & CO. KGAA (DE) | 2011-10-27 | — | — | WO | disclosed |
| WO-2011006689-A2 | COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT | HENKEL AG & CO. KGAA (DE) | 2011-01-20 | — | — | WO | disclosed |
| WO-2011003641-A2 | DEODORANTS AND ANTIPERSPIRANTS HAVING AGENTS MINIMIZING OR INHIBITING HAIR GROWTH | HENKEL AG & CO. KGAA (DE) | 2011-01-13 | — | — | WO | disclosed |
| WO-2007131286-A1 | NANOSTRUCTURES SUITABLE FOR DELIVERY OF AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-11-22 | — | — | WO | disclosed |
| US-20070243132-A1 | Transdermal delivery of pharmaceutical agents | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-10-18 | — | — | US | disclosed |
| EP-0397409-A1 | The stabilization of organic compounds | BTG INTERNATIONAL LIMITED (GB) | 1990-11-14 | — | — | EP | disclosed |
| EP-0305646-A2 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |
| EP-0120670-B1 | IRON III COMPLEXES OF HYDROXYPYRIDONES, AND THEIR PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | disclosed |