SCHEMBL439446

SCHEMBL439446

Clc1cc(-c2ccccc2)c2ccc3c(-c4ccccc4)cc(Cl)nc3c2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
LMNA P02545 2/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
MAPK1 P28482 1/20 0.41
METAP2 P50579 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.40
MPI P34949 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP1A2 P05177 2/20 0.38
ADORA1 P30542 2/20 0.38
CYP2C19 P33261 2/20 0.38
GMNN O75496 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31046570 1.00 KDM4E (0.43) KDM4ELMNAHSP90AA1HSP90AB1MAPK1
SCHEMBL440401 0.93 KDM4E (0.41) KDM4ELMNAHSP90AA1HSP90AB1MAPK1
SCHEMBL30866395 0.93 KDM4E (0.50) KDM4ELMNAHSP90AA1HSP90AB1MAPK1
SCHEMBL17973332 0.90 LMNA (0.51) KDM4ELMNAHSP90AA1HSP90AB1MAPK1
SCHEMBL17396322 0.88 TOP2A (0.41) KDM4ELMNAHSP90AA1HSP90AB1MAPK1
SCHEMBL23406925 0.87 KDM4E (0.41) KDM4ELMNAHSP90AA1HSP90AB1MAPK1
SCHEMBL22686770 0.87 CCR1 (0.48) KDM4ELMNAHSP90AA1ALDH1A1HPGD
SCHEMBL31096890 0.87 CCR1 (0.48) KDM4ELMNAHSP90AA1ALDH1A1HPGD
SCHEMBL23406889 0.86 ADORA1 (0.44) KDM4ELMNAALDH1A1HPGDL3MBTL1
SCHEMBL18092547 0.84 KDM4E (0.43) KDM4EHSP90AA1HSP90AB1MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271313-A Organic compound with symmetrical structure, application of organic compound and perovskite solar cell 北京绿人科技有限责任公司 2024-07-02 CN disclosed
CN-115894494-B Ligand, complex and application thereof in electrochemical reaction 南方科技大学 2024-06-18 CN disclosed
WO-2024014934-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-01-18 WO disclosed
WO-2023153905-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2023-08-17 WO disclosed
CN-115894494-A Ligand, complex and application in electrochemical reaction 南方科技大学 2023-04-04 CN disclosed
US-11578088-B2 Organic compound, an electron transport material and an application thereof XIAMEN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-02-14 US disclosed
US-20200270280-A1 ORGANIC COMPOUND, AN ELECTRON TRANSPORT MATERIAL AND AN APPLICATION THEREOF XIAMEN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-08-27 US disclosed
CN-107619468-B Conjugated polymer of ferrocene and phenanthroline derivative and polymerization method and application thereof 浙江工业大学义乌科学技术研究院有限公司 2020-04-07 CN disclosed
US-9768390-B2 Phenanthroline derivative for organic electroluminescent device LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-09-19 US disclosed
US-9768390-B2 Phenanthroline derivative for organic electroluminescent device LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-09-19 US disclosed
US-20100207108-A1 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-19 US disclosed
US-20100207108-A1 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-19 US disclosed
WO-2010075421-A2 ELECTRONIC DEVICES HAVING LONG LIFETIME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010075421-A2 ELECTRONIC DEVICES HAVING LONG LIFETIME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010075411-A2 PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010075411-A2 PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010075379-A2 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010075379-A2 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010068865-A2 PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-17 WO disclosed
WO-2010068865-A2 PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11578088-B2 Organic compound, an electron transport material and an application thereof OCIAD1, OCIAD2, SLCO4C1 KDM4E 2749/4885LMNA 2298/4885HSP90AA1 4867/4885
US-20100207108-A1 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE PAH, AHR, TYR KDM4E 1156/4885LMNA 2873/4885HSP90AA1 3088/4885
US-20200270280-A1 ORGANIC COMPOUND, AN ELECTRON TRANSPORT MATERIAL AND AN APPLICATION THEREOF OCIAD1, OCIAD2, SLCO4C1 KDM4E 2749/4885LMNA 2298/4885HSP90AA1 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.