Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 7/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 3/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394175 | 0.78 | LMNA (0.42) | GLRA3GLRBALDH1A1GAATDP1 | |
| SCHEMBL30893094 | 0.76 | GLRA3 (0.52) | GLRA3GLRBALDH1A1GAATDP1 | |
| SCHEMBL5000262 | 0.76 | GLRA3 (0.52) | GLRA3GLRBALDH1A1GAATDP1 | |
| SCHEMBL11631722 | 0.74 | NR5A2 (0.46) | GLRA3GLRBALDH1A1GAATDP1 | |
| SCHEMBL4391183 | 0.72 | MAOB (0.40) | GLRA3GLRBCNR2ALDH1A1GAA | |
| SCHEMBL8605774 | 0.71 | GAA (0.35) | GLRA3GLRBALDH1A1GAATDP1 | |
| SCHEMBL8605885 | 0.71 | NR5A2 (0.46) | GLRA3GLRBALDH1A1GAATDP1 | |
| SCHEMBL29477956 | 0.70 | SMN1; SMN2 (0.41) | GLRA3GLRBALDH1A1GAATDP1 | |
| Potassium Ion SCHEMBL29477999 | 0.70 | SMN1; SMN2 (0.41) | GLRA3GLRBALDH1A1GAATDP1 | |
| SCHEMBL8605769 | 0.69 | NR5A2 (0.50) | GAACA2NR5A2NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132453-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-11-05 | — | — | WO | disclosed |