Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL4395724 | 1.00 | KMT2A (0.56) | KMT2AALOX15BLMPMP22NOD1 | |
| SCHEMBL13585297 | 0.94 | NOD1 (0.58) | KMT2ANOD1FOLH1ALDH1A1PTGS1 | |
| SCHEMBL13585300 | 0.94 | NOD1 (0.58) | KMT2ANOD1FOLH1ALDH1A1PTGS1 | |
| SCHEMBL9628017 | 0.94 | NOD1 (0.58) | KMT2ANOD1FOLH1ALDH1A1PTGS1 | |
| SCHEMBL234160 | 0.94 | NOD1 (0.58) | KMT2ANOD1FOLH1ALDH1A1PTGS1 | |
| SCHEMBL234161 | 0.94 | NOD1 (0.58) | KMT2ANOD1FOLH1ALDH1A1PTGS1 | |
| D-Glutamate SCHEMBL4393018 | 0.90 | FOLH1 (0.60) | NOD1FOLH1ALDH1A1PTGS1GSTK1 | |
| Glutamic Acid SCHEMBL4393021 | 0.90 | FOLH1 (0.60) | NOD1FOLH1ALDH1A1PTGS1GSTK1 | |
| Aspartic Acid SCHEMBL4390861 | 0.87 | NOD1 (0.52) | NOD1FOLH1ALDH1A1PTGS1GSTK1 | |
| Aspartic Acid SCHEMBL4390865 | 0.87 | NOD1 (0.52) | NOD1FOLH1ALDH1A1PTGS1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10175233-B2 | Biomarkers for cardiovascular diseases and methods using the same | METABOLON, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20160178620-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2016-06-23 | — | — | US | disclosed |
| US-9250225-B2 | Biomarkers for insulin resistance and methods using the same | METABOLON, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150005195-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2015-01-01 | — | — | US | disclosed |
| US-8809008-B2 | Biomarkers for impaired glucose tolerance and methods using the same | METABOLON, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130338031-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2013-12-19 | — | — | US | disclosed |
| EP-2164977-B1 | BIOMARKERS FOR PRE-DIABETES AND METHODS USING THE SAME | METABOLON INC (US) | 2013-10-30 | — | — | EP | disclosed |
| US-8546098-B2 | Biomarkers for monitoring insulin resistance and methods using the same | METABOLON, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120208215-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8187830-B2 | Method for determining insulin sensitivity with biomarkers | METABOLON, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090155826-A1 | Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same | METABOLON, INC. (US) | 2009-06-18 | — | — | US | disclosed |