Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 11/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1382740 | 0.95 | TPSAB1 (0.61) | TPSAB1 | |
| SCHEMBL1381265 | 0.89 | TPSAB1 (0.58) | TPSAB1PARP10PARP14 | |
| Hydrochloric Acid SCHEMBL4412707 | 0.88 | TPSAB1 (0.52) | TPSAB1 | |
| Hydrochloric Acid SCHEMBL4408179 | 0.88 | TPSAB1 (0.57) | TPSAB1PARP10PARP14 | |
| SCHEMBL1384004 | 0.84 | TPSAB1 (0.52) | TPSAB1 | |
| Hydrochloric Acid SCHEMBL4404661 | 0.83 | TPSAB1 (0.52) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4411930 | 0.83 | TPSAB1 (0.59) | TPSAB1 | |
| SCHEMBL16771622 | 0.82 | TPSAB1 (0.57) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4412795 | 0.82 | TPSAB1 (0.59) | TPSAB1 | |
| Hydrochloric Acid SCHEMBL4396157 | 0.80 | TPSAB1 (0.58) | TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296972-B1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-12-23 | — | — | EP | claimed |