SCHEMBL4396584

SCHEMBL4396584

CCC(CO)(CO)CO.OCC(CO)(CO)COCC(CO)(CO)CO

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
ALDH1A1 P00352 2/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17460096 1.00 THRB (0.35) THRBALDH1A1TSHR
SCHEMBL28077509 0.97 THRB (0.34) THRB
SCHEMBL17460095 0.94 THRB (0.35) THRBALDH1A1TSHR
SCHEMBL13616508 0.94 THRB (0.35) THRBALDH1A1TSHR
SCHEMBL14022830 0.92 THRB (0.34) THRB
SCHEMBL12191395 0.92 THRB (0.34) THRB
SCHEMBL10089424 0.92 THRB (0.36) THRBALDH1A1TSHR
SCHEMBL45482 0.92 THRB (0.36) THRBALDH1A1TSHR
SCHEMBL7113288 0.89 THRB (0.35) THRBALDH1A1TSHR
SCHEMBL21291961 0.89 THRB (0.35) THRBALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1667745-B1 LUBRICIOUS COATING BOSTON SCIENT LTD (BB) 2009-12-16 EP claimed
CN-1124372-C Liquid crystal polymer monofilament having adhesion improved CELANESE ASIDETT LLC CO (US) 2003-10-15 CN claimed
CN-109561953-B Degradable bone adhesives based on phosphorylated poly (ester-ureas) 阿克伦大学 2021-12-21 CN disclosed
CN-111093723-A Poly (ester ureas) for shape memory and drug delivery 阿克伦大学 2020-05-01 CN disclosed
EP-3140340-B1 RADIOOPAQUE, IODINE FUNCTIONALIZED PHENYLALANINE-BASED POLY(ESTER UREA)S UNIV AKRON (US) 2019-07-10 EP disclosed
WO-2017189534-A1 PHOSPHORYLATED POLY(ESTER-UREA) BASED DEGRADABLE BONE ADHESIVES THE UNIVERSITY OF AKRON (US) 2017-11-02 WO disclosed
EP-3142610-A1 MODULAR DEVICE FOR PREVENTING COMPRESSION AND INSTABILITY IN A SEGMENTAL DEFECT REPAIR SCAFFOLD Becker, Matthew (US) 2017-03-22 EP disclosed
EP-3140340-A1 RADIOOPAQUE, IODINE FUNCTIONALIZED PHENYLALANINE-BASED POLY(ESTER UREA)S The University of Akron (US) 2017-03-15 EP disclosed
WO-2015175637-A1 MODULAR DEVICE FOR PREVENTING COMPRESSION AND INSTABILITY IN A SEGMENTAL DEFECT REPAIR SCAFFOLD BECKER MATTHEW (US) 2015-11-19 WO disclosed
WO-2015171854-A1 RADIOOPAQUE, IODINE FUNCTIONALIZED PHENYLALANINE-BASED POLY(ESTER UREA)S THE UNIVERSITY OF AKRON (US) 2015-11-12 WO disclosed
CN-1124372-C Liquid crystal polymer monofilament having adhesion improved CELANESE ASIDETT LLC CO (US) 2003-10-15 CN disclosed
CN-1255558-A Liquid crystal polymer monofilament having adhesion improved CELANESE ASIDETT LLC CO (US) 2000-06-07 CN disclosed
EP-0363460-B1 EPOXY-AMINE COMPOSITIONS EMPLOYING UNSATURATED IMIDES LOCTITE CORP (US) 1993-12-22 EP disclosed
EP-0363460-A1 EPOXY-AMINE COMPOSITIONS EMPLOYING UNSATURATED IMIDES. LOCTITE CORP (US) 1990-04-18 EP disclosed
US-4886842-A PHOTOCURABLE BLEND; HEAT-RESISTANT ADHESIVES FOR ELECTRICAL COMPONENTS LOCTITE CORPORATION (US) 1989-12-12 US disclosed
WO-1989008122-A1 EPOXY-AMINE COMPOSITIONS EMPLOYING UNSATURATED IMIDES LOCTITE CORPORATION (US) 1989-09-08 WO disclosed
US-4837295-A IMPROVED INITIAL ADHESION AND THERMAL SHOCK RESISTANCE LOCTITE CORPORATION (US) 1989-06-06 US disclosed