Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634586 | 0.80 | NPC1 (0.56) | NPC1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL3456922 | 0.80 | MEN1 (0.61) | TDP1SMN1; SMN2KMT2AMEN1L3MBTL1 | |
| SCHEMBL4404236 | 0.73 | EPHX2 (0.52) | THRBNPC1KMT2AMEN1RAB9A | |
| SCHEMBL4117717 | 0.73 | CNR2 (0.61) | TDP1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL28854265 | 0.70 | MEN1 (0.65) | TDP1NPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27581546 | 0.70 | MEN1 (0.60) | TDP1NPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL19808478 | 0.69 | EPHX2 (0.66) | KMT2AL3MBTL1 | |
| SCHEMBL4784023 | 0.68 | RAB9A (0.66) | TDP1NPC1KMT2AMEN1RAB9A | |
| SCHEMBL1569293 | 0.68 | TSHR (0.80) | TDP1NPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29535471 | 0.68 | TSHR (0.80) | TDP1NPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796657-B1 | N-2 ADAMANTANYL-2-PHENOXY-ACETAMIDE DERIVATIVES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-23 | — | — | EP | claimed |