SCHEMBL4396741

SCHEMBL4396741

CCCCCC1(CCCC)OO1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
THRB P10828 1/20 0.39
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.33
DNM1 Q05193 7/20 0.32
SLC22A1 O15245 2/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825612 0.94 TSHR (0.39) TSHRTHRBHTTLMNADNM1
SCHEMBL9849478 0.94 TSHR (0.38) TSHRTHRBHTTLMNA
SCHEMBL19586815 0.92 TSHR (0.37) TSHRTHRBHTTLMNADNM1
SCHEMBL9849353 0.89 TSHR (0.42) TSHRTHRBHTTLMNADNM1
SCHEMBL16829062 0.88 TSHR (0.33) TSHRTHRBLMNA
SCHEMBL3929951 0.86 TSHR (0.37) TSHRTHRBHTTLMNADNM1
SCHEMBL9849421 0.83 TSHR (0.42) TSHRTHRBHTTLMNADNM1
SCHEMBL14058730 0.83 TSHR (0.42) TSHRTHRBHTTLMNADNM1
SCHEMBL7333127 0.83 TSHR (0.42) TSHRTHRBHTTLMNADNM1
SCHEMBL14777983 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249947-B Rubber composition for fuel cell cooling tube and fuel cell cooling tube using the same 现代自动车株式会社 2024-03-15 CN claimed
JP-62133667-A None JP disclosed
WO-2022085700-A1 3D MODELING MATERIAL, RESIN MOLDED BODY AND METHOD FOR PRODUCING SAME 三菱ケミカル株式会社 2022-04-28 WO disclosed
US-20090014965-A1 Sealing material NOK CORPORATION (JP) 2009-01-15 US disclosed
US-20070225448-A1 Sealing material KUDO MASASHI 2007-09-27 US disclosed
US-20070221448-A1 Sealing material KUDO MASASHI 2007-09-27 US disclosed
US-20060155074-A1 Sealing material NOK CORPORATION (JP) 2006-07-13 US disclosed
EP-1548085-A1 SEALING MATERIAL NOK Corporation (JP) 2005-06-29 EP disclosed
EP-0927225-B1 VEHICLE POWER TRANSMISSION BELTS EXXONMOBIL CHEM PATENTS INC (US) 2002-07-03 EP disclosed
EP-1121385-A1 ELASTOMERIC POLYMER VEHICLE PARTS HAVING IMPROVED LOW-TEMPERATURE COMPRESSION SET ExxonMobil Chemical Patents Inc. (US) 2001-08-08 EP disclosed
US-5698650-A ETHYLENE, APHA-OLEFIN-VINYLNORBORNENE TERPOLYMER EXXON CHEMICAL PATENTS INC. (US) 1997-12-16 US disclosed
WO-1997000291-A1 IMPROVED ELASTOMERIC EXTRUDED PROFILES EXXON CHEMICAL PATENTS INC. (US) 1997-01-03 WO disclosed
WO-1997000290-A1 ELASTOMERIC VEHICLE VIBRATION DAMPING DEVICES EXXON CHEMICAL PATENTS INC. (US) 1997-01-03 WO disclosed
WO-1997000289-A1 ELASTOMERIC VEHICLE BRAKE PARTS EXXON CHEMICAL PATENTS INC. (US) 1997-01-03 WO disclosed
US-5571883-A MOTOR VEHICLE ENGINE MOUNTS, TRANSMISSION MOUNTS, ETC.; ETHYLENE, OLEFIN, VINYL NORBORNENE TERPOLYMER EXXON CHEMICAL PATENTS INC. (US) 1996-11-05 US disclosed
US-4904761-A GRAFT COPOLYMER OF A EPOXY RESIN AND VINYL POLYMER HAVING DISPERSED FINE PARTICLES OF SILICONE RUBBER MITSUI TOATSU CHEMICALS, INC. (JP) 1990-02-27 US disclosed
EP-0280437-A1 Elastomer roll having a first layer of an organopolysiloxane composition and a second thin layer of a fluorine resin Shin-Etsu Chemical Co., Ltd. (JP) 1988-08-31 EP disclosed
EP-0139043-B1 VULCANIZABLE POLYMERIC COMPOSITIONS CONTAINING A ZINC DIMETHACRYLATE ADJUVANT AND METHOD FOR PREPARING THE ADJUVANT THE FIRESTONE TIRE & RUBBER COMPANY (US) 1988-04-06 EP disclosed
JP-S62133667-A SAFETY VALVE RUBBER NIPPON TELEGR & TELEPH CORP <NTT> 1987-06-16 JP disclosed
EP-0168020-A2 Fluorinated thermoplastic elastomer compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-15 EP disclosed