Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 19/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 17/20 | 0.62 |
| ▸ | DRD2 | P14416 | 14/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7199889 | 0.99 | DRD3 (0.61) | DRD3KCNH2DRD2MEN1NPC1 | |
| SCHEMBL4378938 | 0.92 | DRD3 (0.63) | DRD3KCNH2DRD2HRH1 | |
| SCHEMBL4390849 | 0.82 | DRD3 (0.62) | DRD3KCNH2DRD2HRH1 | |
| Hydrochloric Acid SCHEMBL7201490 | 0.81 | DRD3 (0.61) | DRD3KCNH2DRD2HRH1 | |
| SCHEMBL4384764 | 0.80 | DRD3 (0.65) | DRD3KCNH2DRD2HRH1 | |
| SCHEMBL4389064 | 0.80 | DRD3 (0.69) | DRD3KCNH2DRD2HRH1 | |
| SCHEMBL4385375 | 0.77 | DRD3 (0.60) | DRD3KCNH2DRD2HRH1 | |
| SCHEMBL4381503 | 0.77 | DRD3 (0.56) | DRD3KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL7202995 | 0.77 | DRD3 (0.59) | DRD3KCNH2DRD2HRH1 | |
| SCHEMBL4387221 | 0.77 | DRD3 (0.62) | DRD3KCNH2DRD2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144405-B1 | TRIAZOLE COMPOUNDS WITH DOPAMINE-D3-RECEPTOR AFFINITY | ABBOTT GMBH & CO KG (DE) | 2009-11-25 | — | — | EP | disclosed |