SCHEMBL4397124

SCHEMBL4397124

CC(Cl)C(Cl)(C(=O)O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TP53 P04637 2/20 0.42
TSHR P16473 2/20 0.42
LMNA P02545 1/20 0.35
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1707413 0.77
Trichloroacetic Acid SCHEMBL5669719 0.75 ALDH1A1 (0.67) ALDH1A1TP53TSHRLMNACYP2C19
SCHEMBL21293007 0.73 ALDH1A1 (0.37) ALDH1A1TP53TSHRLMNA
SCHEMBL11400403 0.72 ALDH1A1 (0.38) ALDH1A1TP53TSHRLMNA
SCHEMBL28581085 0.72
SCHEMBL350604 0.71
SCHEMBL10926326 0.70 ALDH1A1 (0.36) ALDH1A1TP53TSHRLMNACYP2C19
Trichloroacetic Acid SCHEMBL8961131 0.69 ALDH1A1 (0.67) ALDH1A1TP53TSHRLMNA
Hydrochloric Acid SCHEMBL9576085 0.69 ALDH1A1 (0.35) ALDH1A1TP53TSHR
SCHEMBL1706942 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719816-B2 Preparing method of polycarbonate GEN ELECTRIC (US) 2009-12-02 EP disclosed
EP-0736574-B1 Thermoplastic resin composition comprising carbonate and acrylic resin GEN ELECTRIC (US) 2004-06-02 EP disclosed
EP-0926118-B1 Process for the purification of bisphenols and preparation of polycarbonates therefrom GEN ELECTRIC (US) 2002-09-11 EP disclosed
EP-0719816-B1 Preparing method of polycarbonate GEN ELECTRIC (US) 2001-05-23 EP disclosed
CN-1065548-C Method for manufacturing polycarbonate GEN ELECTRIC (US) 2001-05-09 CN disclosed
CN-1065549-C Preparing method of polycarbonate GEN ELECTRIC (US) 2001-05-09 CN disclosed
US-6103827-A A TRANSPARENT THERMOPLASTIC RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2000-08-15 US disclosed
EP-0694572-B1 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2000-05-10 EP disclosed
EP-0719814-B1 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2000-05-10 EP disclosed
EP-0719815-B1 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2000-05-03 EP disclosed
EP-0736574-A2 Thermoplastic resin composition comprising carbonate and acrylic resin GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
CN-1130649-A Method for manufacturing polycarbonate GEN ELECTRIC (US) 1996-09-11 CN disclosed
CN-1130647-A Method for manufacturing polycarbonate GEN ELECTRIC (US) 1996-09-11 CN disclosed
CN-1129717-A Preparing method of polycarbonate GEN ELECTRIC (US) 1996-08-28 CN disclosed
EP-0719816-A2 Preparing method of polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-07-03 EP disclosed
EP-0719814-A2 A method for manufacturing polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-07-03 EP disclosed
EP-0719815-A2 A method for manufacturing polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-07-03 EP disclosed
EP-0694572-A2 A method for manufacturing polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed
EP-0694582-A2 A glass-fiber-reinforced polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed
EP-0694581-A2 A polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed