Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388224 | 1.00 | HTT (0.43) | HTTMAPTRXFP1MBOAT4ALDH1A1 | |
| SCHEMBL4393832 | 1.00 | HTT (0.43) | HTTMAPTRXFP1MBOAT4ALDH1A1 | |
| SCHEMBL4395384 | 1.00 | HTT (0.43) | HTTMAPTRXFP1MBOAT4ALDH1A1 | |
| SCHEMBL4383964 | 1.00 | HTT (0.43) | HTTMAPTRXFP1MBOAT4ALDH1A1 | |
| SCHEMBL4388761 | 0.99 | HTT (0.44) | HTTMAPTRXFP1MBOAT4ALDH1A1 | |
| SCHEMBL4389939 | 0.83 | TSHR (0.51) | MAPTRXFP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4388772 | 0.83 | TSHR (0.51) | MAPTRXFP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4389706 | 0.83 | TSHR (0.51) | MAPTRXFP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4381331 | 0.83 | TSHR (0.51) | MAPTRXFP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4389684 | 0.83 | TSHR (0.51) | MAPTRXFP1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629383-B2 | Double esters | DRUG DISCOVERY LABORATORY AS (NO) | 2009-12-08 | — | — | US | disclosed |
| US-20050203181-A1 | Double esters | DRUG DISCOVERY LABORATORY AS (NO) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203181-A1 | Double esters | ACACA, CES1, ACACB | HTT 3554/4885MAPT 4589/4885RXFP1 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.