SCHEMBL4397183

SCHEMBL4397183

C1COC(CCOCCC2=NCCO2)=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11783308 0.98
SCHEMBL9917633 0.89
SCHEMBL12086389 0.88
SCHEMBL17923541 0.87 TSHR (0.38)
SCHEMBL351538 0.83 ADRA2A (0.34)
SCHEMBL8040746 0.83
SCHEMBL21098619 0.82
SCHEMBL2759296 0.80
SCHEMBL11709160 0.79
SCHEMBL31325987 0.79 POLB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4056502-A ABSORBENT ARTICLES MADE FROM CARBOXYLIC POLYELECTROLYTE SOLUTIONS CONTAINING BIS-OXAZOLINE CROSSLINKER AND METHODS FOR THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 1977-11-01 US claimed
US-8816004-B2 Oxazolinyl-containing polymers and grafted compounds prepared from the oxazolinyl-containing polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-08-26 US disclosed
EP-2651984-A2 OXAZOLINYL-CONTAINING POLYMERS AND GRAFTED COMPOUNDS PREPARED FROM THE OXAZOLINYL-CONTAINING POLYMERS 3M Innovative Properties Company (US) 2013-10-23 EP disclosed
US-20130253137-A1 OXAZOLINYL-CONTAINING POLYMERS AND GRAFTED COMPOUNDS PREPARED FROM THE OXAZOLINYL-CONTAINING POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-26 US disclosed
US-8268937-B2 Crosslinkable aramid copolymers TEIJIN ARAMID B.V. (NL) 2012-09-18 US disclosed
WO-2012082487-A2 OXAZOLINYL-CONTAINING POLYMERS AND GRAFTED COMPOUNDS PREPARED FROM THE OXAZOLINYL-CONTAINING POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-06-21 WO disclosed
US-20090318660-A1 CROSSLINKABLE ARAMID COPOLYMERS TEIJIN ARAMID B.V. (NL) 2009-12-24 US disclosed
EP-2064289-A2 CROSSLINKABLE ARAMID COPOLYMERS Teijin Aramid B.V. (NL) 2009-06-03 EP disclosed
WO-2008028605-A2 CROSSLINKABLE ARAMID COPOLYMERS TEIJIN ARAMID B.V. (NL) 2008-03-13 WO disclosed
US-4056502-A ABSORBENT ARTICLES MADE FROM CARBOXYLIC POLYELECTROLYTE SOLUTIONS CONTAINING BIS-OXAZOLINE CROSSLINKER AND METHODS FOR THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 1977-11-01 US disclosed
US-3996237-A Oxazoline- or oxazine-substituted acrylic esters THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed
US-RE29027-E Reaction products of polyepoxide and excess di-2-oxazoline THE DOW CHEMICAL COMPANY (US) 1976-11-02 US disclosed