Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | TST | Q16762 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478307 | 0.81 | MAPT (0.67) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL1934664 | 0.81 | MAPT (0.67) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL11381977 | 0.81 | MAPT (0.67) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL1197734 | 0.81 | MAPT (0.67) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL20875134 | 0.81 | MAPT (0.67) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL20875130 | 0.81 | MAPT (0.67) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL23356552 | 0.81 | MAPT (0.70) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL285433 | 0.81 | MAPT (0.70) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL7867820 | 0.80 | MAPT (0.65) | TDP1HSPD1HSPE1TSTMAPT | |
| SCHEMBL4388035 | 0.74 | MAPT (0.55) | TDP1HSPD1HSPE1TSTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | claimed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | claimed |
| WO-2007070092-A2 | METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME | PRYOG, LLC (US) | 2007-06-21 | — | — | WO | claimed |
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | disclosed |