1,4-Dichlorobenzene

1,4-Dichlorobenzene

SCHEMBL4397293

Clc1ccc(Cl)cc1.O=[N+]([O-])C(Cl)(Cl)Cl

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.61
FBP1 P09467 2/20 0.46
LMNA P02545 3/20 0.44
CYP2A6 P11509 1/20 0.44
MAPK1 P28482 4/20 0.43
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
HIF1A Q16665 2/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL6047149 0.82 TSHR (0.41) TSHRFBP1LMNAMAPK1ALDH1A1
Chloropicrin SCHEMBL604956 0.78 TSHR (1.00) TSHRLMNAALDH1A1TDP1CA5A
Chloropicrin SCHEMBL75169 0.78
1,4-Dichlorobenzene SCHEMBL29002852 0.77 FBP1 (0.52) TSHRFBP1LMNACYP2A6MAPK1
1,4-Dichlorobenzene SCHEMBL28182719 0.77 FBP1 (0.50) TSHRFBP1LMNACYP2A6MAPK1
Chloropicrin SCHEMBL27335999 0.76 TSHR (0.79) TSHRFBP1LMNAALDH1A1TDP1
Chloropicrin SCHEMBL31207791 0.75
Chloropicrin SCHEMBL28145121 0.75
Chloropicrin SCHEMBL10611964 0.75
SCHEMBL29242 0.72 CYP1A2 (0.67) LMNAALDH1A1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090305071-A1 Fluoro-compound water repellent composition for wood product dimensional stability ZHANG JUN 2009-12-10 US disclosed
US-20070160850-A1 Fluoro-compound water repellent composition for wood product dimensional stability OSMOSE, INC. (US) 2007-07-12 US disclosed
US-20060100340-A1 Polymer and water repellent compositions for wood product dimensional stability OSMOSE, INC. 2006-05-11 US disclosed