SCHEMBL439730

SCHEMBL439730

O=C(O)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
SCN2A Q99250 1/20 0.48
KMT2A Q03164 3/20 0.47
POLB P06746 3/20 0.47
ASAH1 Q13510 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 2/20 0.45
EHMT2 Q96KQ7 1/20 0.45
EHMT1 Q9H9B1 1/20 0.45
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 1/20 0.44
CYP2C9 P11712 1/20 0.44
CES1 P23141 1/20 0.44
KDM4E B2RXH2 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30704939 1.00 CA12 (0.54) CA12CA9CA1CA2SCN2A
Ammonia Solution, Strong SCHEMBL11349044 0.98 CA12 (0.52) CA12CA9CA1CA2SCN2A
Ammonia Solution, Strong SCHEMBL11349034 0.98 CA12 (0.52) CA12CA9CA1CA2SCN2A
Hydrochloric Acid SCHEMBL9592305 0.98 CA12 (0.52) CA12CA9CA1CA2SCN2A
SCHEMBL27088462 0.85 CA12 (0.46) CA12CA9CA1CA2SCN2A
SCHEMBL21855119 0.84 CA12 (0.52) CA12CA9CA1CA2SCN2A
SCHEMBL23732653 0.83 CA12 (0.52) CA12CA9CA1CA2SCN2A
SCHEMBL238006 0.82 CA12 (0.50) CA12CA9CA1CA2SCN2A
SCHEMBL29120364 0.81 ERCC1 (0.62) CA12CA9KMT2APOLBCYP1A2
SCHEMBL29763759 0.80 HNF4A (0.44) CA12CA9KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111018664-B Synthesis method of 2-alkyl-1, 3-propanediol compound 江苏广域化学有限公司 2023-04-14 CN claimed
CN-111018664-A Synthesis method of 2-alkyl-1, 3-propanediol compound 江苏广域化学有限公司 2020-04-17 CN claimed
CN-110526817-A A kind of synthetic method of m-methyl benzoic acid WUXUE YANGTAI CHEMICAL CO LTD 2019-12-03 CN claimed
CN-110526819-A A kind of synthetic method of terephthalic acid (TPA) WUXUE YANGTAI CHEMICAL CO LTD 2019-12-03 CN claimed
CN-110526816-A A kind of synthetic method of M-phthalic acid WUXUE YANGTAI CHEMICAL CO LTD 2019-12-03 CN claimed
CN-110526815-A A kind of synthetic method of p-methylbenzoic acid WUXUE YANGTAI CHEMICAL CO LTD 2019-12-03 CN claimed
CN-109603415-A Laboratory exhaust gas adsorption tower 广州九诺实业有限公司 2019-04-12 CN claimed
CN-108384221-A A kind of electronic material and preparation method thereof with high dielectric property 合肥励仙电力工程有限公司 2018-08-10 CN claimed
CN-108384172-A A kind of dystectic electronic material and preparation method thereof 合肥励仙电力工程有限公司 2018-08-10 CN claimed
CN-107498967-A Easily-processed heat-insulating composite material and preparation method thereof 嘉兴立新材料有限公司 2017-12-22 CN claimed
CN-107222884-A A kind of communication base station integration testing switch-box 苏州永安丰新能源科技有限公司 2017-09-29 CN claimed
CN-104151473-B Modification type styrene maleic anhydride copolymer and its compositions of thermosetting resin 苏州生益科技有限公司 2017-03-15 CN claimed
CN-101781540-B High-performance conducting resin and preparation method thereof UNIV DONGHUA 2013-03-06 CN claimed
WO-2012106169-A1 METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 2012-08-09 WO claimed
US-20120192741-A1 METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATES NPEC INC. 2012-08-02 US claimed
CN-101781540-A High-performance conducting resin and preparation method thereof UNIV DONGHUA 2010-07-21 CN claimed
US-20070039874-A1 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY 2007-02-22 US claimed
EP-0354881-B1 ACETAZOLAMIDE-RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME ISTITUTO CHIMICO INTERNAZIONALE DR. GIUSEPPE RENDE S.R.L. (IT) 1992-04-22 EP claimed
EP-0354881-A1 Acetazolamide-related compounds, process for their preparation, and pharmaceutical composition containing the same ISTITUTO CHIMICO INTERNAZIONALE DR. GIUSEPPE RENDE S.R.L. (IT) 1990-02-14 EP claimed
EP-0214112-A2 Polyester compositions containing phthalimidoesters Monsanto Company (US) 1987-03-11 EP claimed