Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 19/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.44 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756240 | 0.88 | DHODH (0.48) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL6859688 | 0.87 | DHODH (0.51) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL6754119 | 0.83 | DHODH (0.46) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL2593220 | 0.82 | AKR1C2 (0.44) | DHODH | |
| SCHEMBL3916870 | 0.77 | F2 (0.40) | DHODHSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19417210 | 0.72 | DHODH (0.65) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL6814731 | 0.70 | DHODH (0.49) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL6813884 | 0.69 | DHODH (0.46) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL18118644 | 0.67 | DHODH (0.83) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL3914186 | 0.67 | DHODH (0.56) | DHODHNR4A2NR4A1JMJD7NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392642-B1 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2009-12-09 | — | — | EP | disclosed |