Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 12/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924667 | 0.77 | DHODH (0.55) | DHODHNR4A2 | |
| SCHEMBL6756240 | 0.74 | DHODH (0.48) | DHODHNR4A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL517774 | 0.74 | DHODH (0.53) | DHODHNR4A2SLC6A3JMJD7NR4A1 | |
| SCHEMBL252179 | 0.74 | DHODH (0.83) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL3924083 | 0.71 | DHODH (0.43) | DHODHNR4A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4397344 | 0.70 | DHODH (0.47) | DHODHNR4A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL517998 | 0.70 | DHODH (0.54) | DHODHSLC6A3MEN1KMT2A | |
| SCHEMBL3914186 | 0.69 | DHODH (0.56) | DHODHNR4A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3926027 | 0.69 | XDH (0.46) | DHODH | |
| SCHEMBL3915763 | 0.69 | OXTR (0.46) | DHODHNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006425-A9 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-02-26 | — | — | WO | disclosed |