SCHEMBL439735

SCHEMBL439735

Cc1cc(N)c2cccc(F)c2n1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.65
TDP1 Q9NUW8 4/20 0.54
KDM4E B2RXH2 3/20 0.54
NCF1 P14598 1/20 0.53
CD38 P28907 2/20 0.42
ADORA2A P29274 3/20 0.40
ADORA1 P30542 2/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
ALDH1A1 P00352 4/20 0.40
LMNA P02545 4/20 0.40
POLB P06746 4/20 0.40
MAPT P10636 4/20 0.40
APEX1 P27695 4/20 0.40
HTT P42858 2/20 0.40
RAB9A P51151 2/20 0.40
PSMD14 O00487 1/20 0.40
MITF O75030 1/20 0.40
HPGD P15428 1/20 0.40
RAD52 P43351 1/20 0.40
GRM2 Q14416 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438224 0.81 NR4A2 (0.69) NR4A2TDP1KDM4ENCF1SMN1; SMN2
SCHEMBL19189304 0.81 KDM4E (0.62) NR4A2TDP1KDM4ECD38SMN1; SMN2
SCHEMBL441540 0.79 NR4A2 (0.51) NR4A2TDP1KDM4ENCF1ADORA2A
SCHEMBL22084269 0.79 KDM4E (0.42) NR4A2TDP1KDM4ECD38ADORA2A
SCHEMBL3051550 0.79 MAPT (0.60) NR4A2TDP1KDM4ECD38LMNA
SCHEMBL5243405 0.79 NR4A2 (0.65) NR4A2TDP1KDM4ENCF1SMN1; SMN2
SCHEMBL439824 0.79 NR4A2 (0.65) NR4A2TDP1KDM4ENCF1CD38
SCHEMBL16506398 0.79 KDM4E (0.42) NR4A2TDP1KDM4ECD38ADORA2A
SCHEMBL438980 0.79 NR4A2 (1.00) NR4A2TDP1KDM4ENCF1CD38
SCHEMBL436969 0.78 NR4A2 (0.46) NR4A2TDP1KDM4ENCF1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529846-A High-performance buffer oxide etching solution and application thereof 湖北兴福电子材料股份有限公司 2025-02-28 CN claimed
CN-119529846-A High-performance buffer oxide etching solution and application thereof 湖北兴福电子材料股份有限公司 2025-02-28 CN disclosed
US-20120065166-A1 Bone Modulators And Methods Therewith ESPINA VIRGINIA (US) 2012-03-15 US disclosed
EP-1150977-B1 PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 2004-08-25 EP disclosed
US-6699879-B1 OBESITY, DIABETES, SLEEP DISORDERS SMITHKLINE BEECHAM P.L.C. (GB) 2004-03-02 US disclosed