Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063558 | 0.83 | NR4A2 (0.71) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL9830968 | 0.81 | NR4A2 (0.69) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL438224 | 0.81 | NR4A2 (0.69) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL5243405 | 0.79 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL439824 | 0.79 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL1026984 | 0.79 | NR4A2 (0.65) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL439768 | 0.79 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL439579 | 0.79 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL439735 | 0.79 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL440270 | 0.76 | NR4A2 (0.62) | NR4A2KDM4ETDP1NCF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596548-A1 | NURR1 MODULATORS | Ludwig-Maximilians-Universität (DE) | 2025-08-06 | — | — | EP | disclosed |
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |
| EP-1150977-B1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2004-08-25 | — | — | EP | disclosed |
| US-6699879-B1 | OBESITY, DIABETES, SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-03-02 | — | — | US | disclosed |
| EP-1150977-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047577-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-08-17 | — | — | WO | disclosed |